‘Smart’ insulin prevents diabetic highs — and deadly lows
https://www.nature.com/articles/d41586-024-03357-7
By Diana Kwon
Scientists have developed a revolutionary insulin that automatically switches on and off based on blood sugar levels, a breakthrough that could transform diabetes management. Known as NNC2215, this “smart” insulin responds to glucose levels in real-time, effectively reducing high blood sugar while preventing dangerous drops that can lead to hypoglycemia. Traditional insulin injections lack this adaptability, putting people with diabetes at risk of complications like seizures or loss of consciousness from low blood sugar. The new insulin was successfully tested in animals and offers hope for a safer, more effective treatment option. Although further research is needed, this innovation could pave the way for personalized diabetes therapies in the future.