The cell rejuvenation atlas: identifying master regulators of rejuvenation strategies
https://www.eurekalert.org/news-releases/1058133
By EurekAlert
Scientists from CIC bioGUNE, LCSB, and Ikerbasque have developed the SINGULAR atlas, a groundbreaking tool that maps out cell rejuvenation strategies at a single-cell level. This new research, published in Aging, dives into how various rejuvenation methods—like calorie restriction and partial reprogramming—affect cellular processes across multiple organs. By using network biology, SINGULAR identifies “master regulators” of rejuvenation, highlighting key targets in immune cells. The goal? To guide future innovations in age reversal treatments. This work opens the door to selecting drugs that can replicate complex anti-aging interventions, pushing forward the science of longevity.